ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
Can you help?
Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet


















Scary, Scarier, Scariest (Part 2): What can YOU do about it?
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
Modeling the value of an effective antibiotic — Megiddo et al.
Lancet: 10-20-30 targets to address AMR by 2030
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
NIAID workshop: What is a robust PK-PD package?
FDA workshop: Insights on inhaled antifungals and antibacterials
FDA analysis of 40-years of antibacterial development: Dheman et al.
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet

The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet